圖 譜 導(dǎo) 讀
**部分 肺臟的基本結(jié)構(gòu)與形態(tài)學(xué)特點
1 肺臟的解剖學(xué)/ 2
2 肺臟的組織形態(tài)學(xué) /3
2.1 肺實質(zhì):導(dǎo)氣部和呼吸部 /3
2.2 肺間質(zhì):肺的血管、淋巴管和神經(jīng)組織/ 6
第二部分 煤工塵肺形態(tài)學(xué)特點
1 煤工塵肺大體形態(tài)學(xué)特點 /8
1.1 煤斑灶:包括胸膜煤斑灶和肺內(nèi)煤斑灶/ 8
1.2 結(jié)節(jié)病變/9
1.3 塊狀纖維化 9
1.4 彌漫性間質(zhì)纖維化/ 9
1.5 肺氣腫病變/ 9
1.6 淋巴結(jié)的病變(多見肺門淋巴結(jié)的累及)/ 10
1.7 胸膜病變 /10
1.8 煤工塵肺伴發(fā)肺結(jié)核病/ 10
1.9 煤工塵肺伴發(fā)肺癌 /10
1.10 煤工塵肺伴發(fā)肺源性心臟病/ 10
2 煤工塵肺組織形態(tài)學(xué)特點/10
2.1 煤矽肺 /10
2.2 矽煤肺(矽肺) /12
2.3 煤肺 /13
2.4 伴發(fā)性病變/ 13
2.5 其他病變 /14
參考文獻 /16
Atlas Guide
Part I Anatomy and Histology of Lung
1 Anatomy of the lung/ 20
2 Histology of the lung/21
2.1 Parenchyma: It includes conduction portion and respiratory portion / 21
2.2 Mesenchyma: It contains blood vessels, lymphatic vessels and nerves / 25
Part II Pathology of Coal Workers' Pneumoconiosis
1 Gross appearance of coal workers' pneumoconiosis/ 27
1.1 Coal dust maculae/27
1.2 Coal dust nodules /28
1.3 Massive fi brosis /28
1.4 Diffuse interstitial fi brosis / 29
1.5 Emphysema /29
1.6 Lesions in the lymph nodes (usually in hilar lymph nodes)/ 29
1.7 Lesions in pleura /29
1.8 Coal works' pneumoconiosis with tuberculosis / 29
1.9 Coal works' pneumoconiosis with lung cancer /30
1.10 Coal works' pneumoconiosis with cor pulmonale /30
2 Histological changes of coal workers' pneumoconiosis/ 30
2.1 Anthracosilicosis/ 30
2.2 Silicosis/32
2.3 Anthracosis/33
2.4 Complicated lesions / 34
2.5 Others /35
References /37
圖譜部分Atlas
**部分 煤工塵肺大體形態(tài)學(xué)特點Part I Gross Appearance of CoalWorkers' Pneumoconiosis
圖1 胸膜煤斑灶/43
Fig.1 Pleural coal dust maculae / 43
圖2 至圖4 肺內(nèi)煤斑灶/43
Fig.2 to Fig.4 Pulmonary coal dust maculae / 43
圖5 肺內(nèi)煤斑灶伴大泡型肺氣腫形成/ 45
Fig.5 Pulmonary coal dust maculae accompanied by bullous emphysema /45
圖6 肺內(nèi)煤斑灶伴囊泡型肺氣腫形成/ 45
Fig.6 Pulmonary coal dust maculae with cystic emphysema / 45
圖7 和圖8 肺內(nèi)煤斑灶(全肺大切片標本) / 46
Fig.7 and Fig.8 Pulmonary coal dust maculae(the large slice) / 46
圖9 和圖10 肺內(nèi)煤斑灶(肺葉大切片標本) / 47
Fig.9 and Fig.10 Pulmonary coal dust maculae(the large slice)/ 47
圖11 和圖12 肺內(nèi)煤斑灶、煤塵纖維灶(煤結(jié)節(jié))形成/ 48
Fig.11 and Fig.12 Pulmonary coal dust maculae and fi brotic lesions( coal dust nodule) / 48
圖13 和圖14 肺內(nèi)煤斑灶、煤矽結(jié)節(jié)/ 49
Fig.13 and Fig.14 Pulmonary coal dust maculae and coal silicotic nodules /49
圖15 和圖16 肺內(nèi)煤斑灶、煤矽結(jié)節(jié)/ 50
Fig.15 and Fig.16 Pulmonary coal dust maculae and coal silicotic nodules/ 50
圖17 和圖18 肺內(nèi)煤斑灶51
Fig.17 and Fig.18 Pulmonary coal dust maculae 51
圖19 和圖20 進行性塊狀纖維化/ 52
Fig.19 and Fig.20 Progressive massive fi brosis/ 52
圖21 和圖22 進行性塊狀纖維化(肺大切片標本) / 53
Fig.21 and Fig.22 Progressive massive fi brosis(the large slice) / 53
圖23 和圖24 結(jié)節(jié)融合型塊狀纖維化/ 54
Fig.23 and Fig.24 Nodular confl uent massive fi brosis / 54
圖25 和圖26 結(jié)節(jié)融合型塊狀纖維化(同圖23 肺大切片標本) / 55
Fig.25 and Fig.26 Nodular confl uent massive fi brosis( this large slice shares the samplewith Fig.23)/55
圖27 和圖28 混合型塊狀纖維化/ 56
Fig.27 and Fig.28 Mixed massive fi brosis / 56
圖29 至圖38 煤工塵肺伴結(jié)核病/ 57
Fig.29 to Fig.38 Coal works' pneumoconiosis with tuberculosis / 57
圖39 煤工塵肺伴肺癌(周圍型) / 62
Fig.39 Coal works' pneumoconiosis with lung cancer( Peripheral type) / 62
圖40 煤工塵肺伴肺癌(彌漫型) / 62
Fig.40 Coal works' pneumoconiosis with lung cancer( Diffuse type)/ 62
圖41 和圖42 煤工塵肺伴胸膜粘連與增厚/ 63
Fig.41 and Fig.42 Coal works' pneumoconiosis with pleural adhesion and thickening/ 63
圖43 和圖44 煤工塵肺合并肺源性心臟病/ 64
Fig.43 and Fig.44 Coal works' pneumoconiosis with cor pulmonale / 64
第二部分 煤工塵肺組織形態(tài)學(xué)特點
Part II Histological Appearance of
Coal Workers' Pneumoconiosis
圖45 至圖48 胸膜煤斑/66
Fig.45 to Fig.48 Coal dust dots of pleura/ 66
圖49 至圖52 肺內(nèi)煤斑/68
Fig.49 to Fig.52 Coal dust dots of lung /68
圖53 和圖54 煤塵細胞灶70
Fig.53 and Fig.54 Cellular coal dust foci / 70
圖55 至圖58 煤塵纖維灶/71
Fig.55 to Fig.58 Fibrous coal dust foci / 71
圖59 至圖74 大小不等、形狀各異的煤塵灶/ 73
Fig.59 to Fig.74 Coal dust lesions varying in size and shape / 73
圖75 至圖78 巨噬細胞性肺泡炎/ 77
Fig.75 to Fig.78 Macrophage alveolitis / 77
圖79 至圖82 煤塵細胞性結(jié)節(jié)/ 79
Fig.79 to Fig.82 Cellular coal dust nodules / 79
圖83 至圖86 細胞纖維性結(jié)節(jié)/ 81
Fig.83 to Fig.86 Cellular fi brous nodules /81
圖87 至圖94 煤矽結(jié)節(jié)/83
Fig.87 to Fig.94 Coal silicotic nodules / 83
圖95 不典型煤矽結(jié)節(jié)/88
Fig.95 Atypical coal silicotic nodule / 88
圖96 至圖103 融合型煤矽結(jié)節(jié)/ 89
Fig.96 to Fig.103 Confl uent coal silicotic nodules/ 89
圖104 矽結(jié)節(jié)/93
Fig.104 Silicotic nodule /93
圖105 融合型矽結(jié)節(jié)/93
Fig.105 Confl uent silicotic nodules / 93
圖106 至圖109 矽結(jié)節(jié)/94
Fig.106 to Fig.109 Silicotic nodule/ 94
圖110 至圖113 進行性塊狀纖維化/ 96
Fig.110 to Fig.113 Progressive massive fi brosis / 96
圖114 和圖115 融合型塊狀纖維化 / 98
Fig.114 and Fig.115 Confl uent massive fi brous lesion / 98
圖116 和圖117 彌漫性塵性間質(zhì)纖維化 / 99
Fig.116 and Fig.117 Diffuse coal interstitial fi brosis/ 99
圖118 和圖119 間質(zhì)纖維化伴平滑肌細胞局灶性增生 / 100
Fig.118 and Fig.119 Interstitial fi brosis with local proliferated smooth muscle cells / 100
圖120 和圖121 煤工塵肺伴結(jié)核病變/101
Fig.120 and Fig.121 Coal workers' pneumoconiosis with tuberculosis / 101
圖122 肺內(nèi)早期煤矽結(jié)核結(jié)節(jié)/ 102
Fig.122 Early stage of coal silicotic tuberculous nodule / 102
圖123 肺內(nèi)典型的煤矽結(jié)核結(jié)節(jié)/ 102
Fig.123 Classic coal silicotic tuberculous nodule / 102
圖124 肺內(nèi)煤矽結(jié)核結(jié)節(jié)/103
Fig.124 Coal silicotic tuberculous nodules/ 103
圖125 至圖127 肺內(nèi)融合型煤矽結(jié)核結(jié)節(jié)/103
Fig.125 to Fig.127 Confl uent coal silicotic tuberculous nodules / 103
圖128 和圖129 煤工塵肺矽結(jié)核結(jié)節(jié)/105
Fig.128 and Fig.129 Silicotic tuberculous nodules of coal works' pneumoconiosis / 105
圖130 結(jié)節(jié)融合型塊狀纖維化/ 106
Fig.130 Nodular confl uent massive fibrosis / 106
圖131 至圖134 煤工塵肺伴播散性粟粒性肺結(jié)核/ 106
Fig.131 to Fig.134 Disseminated miliary tuberculosis of coal workers' pneumoconiosis / 106
圖135 塵性結(jié)核性結(jié)節(jié)/108
Fig.135 Coal dust tuberculous nodules / 108
圖136 和圖137 塵性結(jié)核性肉芽腫(結(jié)節(jié))/ 109
Fig.136 and Fig.137 Coal dust tuberculous granuloma( nodule) / 109
圖138 和圖139 塵性結(jié)核性支氣管炎/ 110
Fig.138 and Fig.139 Coal dust tuberculous bronchiolitis / 110
圖140 煤工塵肺伴結(jié)核性胸膜炎/ 111
Fig.140 Tuberculous pleuritis of coal workers' pneumoconiosis / 111
圖141 煤工塵肺結(jié)核性空洞/ 111
Fig. 141 Tuberculous cavity of coal workers' pneumoconiosis . 111
圖142 和圖143 煤工塵肺伴發(fā)肺腺癌/ 112
Fig.142 and Fig.143 Coal workers' pneumoconiosis with pulmonary adenocarcinoma / 112
圖144 和圖145 煤工塵肺伴淋巴結(jié)轉(zhuǎn)移腺癌/ 113
Fig.144 and Fig.145 Coal workers' pneumoconiosis with lymph node adenocarcinoma metastasis / 113
圖146 和圖147 煤工塵肺伴發(fā)肺腺癌/ 114
Fig.146 and Fig.147 Coal workers' pneumoconiosis with pulmonary adenocarcinoma / 114
圖148 至圖151 煤工塵肺伴發(fā)腺鱗癌/ 115
Fig.148 to Fig151 Coal workers' pneumoconiosis with pulmonary adenosquamous carcinoma / 115
圖152 和圖153 煤工塵肺伴發(fā)惡性間皮瘤/117
Fig.152 and Fig.153 Coal workers' pneumoconiosis with malignant mesothelioma/ 117
圖154 煤工塵肺伴發(fā)惡性間皮瘤淋巴結(jié)轉(zhuǎn)移/ 118
Fig.154 Coal workers' pneumoconiosis with lymph node malignant mesothelioma
metastasis 118
圖155 血管內(nèi)瘤栓形成118
Fig.155 Carcinoma cells emboli in small blood vessels / 118
圖156 至圖159 淋巴結(jié)煤塵沉積. 119
Fig.156 to Fig.159 Lymph nodes with coal dust deposition . 119
圖160 至圖163 淋巴結(jié)內(nèi)煤矽結(jié)節(jié). 121
Fig.160 to Fig.163 Coal silicotic nodules in lymph nodes / 121
圖164 淋巴結(jié)病變/123
Fig.164 Silicotic lesions in lymph nodes/ 123
圖165 至圖167 淋巴結(jié)內(nèi)矽結(jié)節(jié)/ 123
Fig.165 to Fig.167 Silicotic nodules in lymph node / 123
圖168 至圖171 淋巴結(jié)內(nèi)融合型矽結(jié)節(jié)/ 125
Fig.168 to Fig.171 Confl uent silicotic nodules in lymph node / 125
圖172 和圖173 淋巴結(jié)內(nèi)煤矽結(jié)核結(jié)節(jié)/ 127
Fig.172 and Fig.173 Coal silicotic tuberculous nodules in lymph nodes / 127
圖174 和圖175 淋巴結(jié)內(nèi)矽結(jié)核結(jié)節(jié). 128
Fig.174 and Fig.175 Silicotic tuberculous nodules in lymph nodes / 128
圖176 至圖180 煤塵侵及支氣管/129
Fig.176 to Fig.180 Coal dust deposition in bronchi /129
圖181 至圖183 塵性慢性細支氣管炎/ 131
Fig.181 to Fig.183 Coal chronic bronchiolitis /131
圖184 至圖189 胸膜病變/133
Fig. 814 to Fig.189 Pleural lesions / 133
圖190 煤塵沉積在肺內(nèi)小支氣管/ 136
Fig.190 Coal dust deposition in small bronchia / 136
圖191 煤塵沉積在肺內(nèi)細支氣管及終末細支氣管/ 136
Fig.191 Coal dust deposition in small bronchia and terminal bronchia / 136
圖192 和圖193 煤塵沉積在呼吸性細支氣管及其分支/ 137
Fig.192 and Fig.193 Coal dust deposition in respiratory bronchia and its branaches /137
圖194 塵性小葉中心型肺氣腫/138
Fig.194 Coal dust-induced centriacinar emphysema /138
圖195 全小葉破壞型肺氣腫/ 138
Fig.195 Destructive panacinar emphysema / 138
圖196 和圖197 累及肺動脈/ 139
Fig.196 and Fig.197 Lesions in pulmonary artery / 139
圖198 肺內(nèi)小動脈病變/140
Fig.198 Lesions in pulmonary small arteries / 140
圖199 肺內(nèi)小血管病變/140
Fig.199 Lesions in pulmonary small vessels / 140
圖200 和圖201 小動脈病變/141
Fig.200 and Fig.201 Lesions in small arteries / 141
圖202 煤塵累及淋巴結(jié)及其脂肪組織/ 142
Fig.202 Coal dust deposits involve lymph nodes and adipose tissue / 142
圖203 煤塵累及支氣管及其周圍脂肪組織/ 142
Fig.203 Involvement of bronchi and adjacent fat tissue by coal dusts / 142
圖204 和圖205 淋巴管病變/ 143
Fig.204 and Fig.205 Lesions in the lymphatic vessels / 143
圖206 和圖207 胸膜下神經(jīng)纖維受累/144
Fig.206 and Fig.207 Coal dusts involve subpleural nerve fi bers / 144
圖208 煤工塵肺伴漿液出血性炎/ 145
Fig.208 Coal workers' pneumoconiosis with serous hemorrhagic infl ammation / 145
圖209 煤工塵肺伴肺水腫/145
Fig.209 Coal workers' pneumoconiosis with pulmonary edema / 145
圖210 和圖211 煤工塵肺伴肺淤血、肺水腫 /146
Fig.210 and Fig.211 Coal workers' pneumoconiosis with pulmonary congestion and edema/ 146
圖212 煤工塵肺伴化膿性炎/ 147
Fig.212 Coal workers pneumoconiosis with purulent infl ammation / 147
圖213 煤工塵肺伴膿腫/147
Fig.213 Coal workers' pneumoconiosis with abscess / 147
圖214 煤工塵肺伴漿液、纖維素性炎/ 148
Fig.214 Coal workers' pneumoconiosis with serous fi brinous infl ammation / 148
圖215 煤工塵肺伴漿液、化膿性炎/ 148
Fig.215 Coal workers' pneumoconiosis with serous purulent infl ammation / 148
圖216 和圖217 煤工塵肺“棒狀小體”形成 /149
Fig.216 and Fig.217 “Rod-shaped” bodies of coal workers' pneumoconiosis / 149
圖218 至圖223 肌成纖維細胞分化/ 150
Fig.218 to Fig.223 Myofi broblasts differentiation / 150
圖224 正常心肌組織(右心室)/ 154
Fig.224 Normal heart tissue( from right ventricle)/ 154
圖225 肺源性心臟病心肌組織(右心室)/ 154
Fig.225 Right ventricle with cor pulmonale / 154
第三部分 煤工塵肺案例
Part III Cases of Coal Workers' Pneumoconiosis
案例一 煤矽肺Ⅰ期(結(jié)節(jié)+ 塵斑- 氣腫) /156
Case 1 Anthracosilicosis(stage Ⅰ,Nodules and maculae surrounded by emphysema) / 157
案例二 煤肺Ⅰ期(煤塵斑灶+ 細胞性結(jié)節(jié)) / 161
Case 2 Anthracosis(stage Ⅰ,Coal dust maculae and cellular nodules) /162
案例三 煤矽肺Ⅱ期(塵斑- 氣腫型) 166
Case 3 Anthracosilicosis( stage Ⅱ,Coal dust maculae and emphysema) / 167
案例四 煤矽肺Ⅲ期(大塊纖維化) / 170
Case 4 Anthracosilicosis(stage Ⅲ,Massive fi brosis) / 171
案例五 煤矽肺Ⅲ期合并肺結(jié)核病/ 176
Case 5 Anthracosilicosis( stage Ⅲ) with pulmonary tuberculosis /177
案例六 煤矽肺Ⅲ期合并肺癌 /182
Case 6 Anthracosilicosis( stage Ⅲ) with lung cancer / 183
案例七 煤肺Ⅰ期(煤斑- 氣腫)合并肺源性心臟 / 189
Case 7 Anthracosis( stage Ⅰ,Coal dust maculae and emphysema) with cor pulmonale /191
后記 /198
Acknowledgement/ 199